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Program

PROGRAM

DAY 01

NOVEMBER 3, 2026
7:30 a.m

Registration

Registration: starting at 7:30 a.m

08:30 – 09:15
Industry Workshops
Merck

Industry Workshops
Cytoniche

09:15 – 09:45

Coffee Break

09:45 – 10:15

Opening Session

Authorities and CEL-GEN / ABTCel-Gen leadership

10:15 – 11:00

President’s Session

Jim Wilson, Gemma Therapeutics

11:00 – 12:00
Grand Rounds

Tumor Infiltrating Lymphocytes
Chairs: to be defined
Tiago da Silva Medina, University of Southern Denmark
Luciana Cavalheiro Marti, Hospital Israelita Albert Einstein

12:00 – 13:30
Industry Workshops
Bio-Manguinhos

Workshop window: 12:30 – 13:15

Industry Workshops
VectorBuilder

Workshop window: 12:30 – 13:15

13:30 – 14:45
INCT-Sponsored Scientific Sessions
RNA Therapies

Chairs: to be defined
Sponsored by CCT-RNA
Mariana Mello, Scripps
Jamile Ramos da Silva, Hospital Israelita Albert Einstein
Santuza Maria Ribeiro Teixeira, UFMG

INCT-Sponsored Scientific Sessions
Advances in Gene Therapy, Cell Therapy and Multiomics

Sponsored by IMASP
Chairs: Roberto Giugliani & Antonio Carlos Campos de Carvalho, HCPA / UFRJ
Jim Wilson, Gemma Therapeutics
Milena Botelho Pereira Soares, Fiocruz-BA
Iscia Lopes-Cendes, UNICAMP

14:45 - 16:00
Scientific Sessions
Viral Delivery

Chairs: to be defined
Veronica Lopez, Fundación Instituto Leloir
Marcio Chaim Bajgelman, CNPEM
Oral Abstract 80: NEUROGENIN 2 overexpression in corticospinal neurons modulates early neuronal and microglial responses after spinal cord injury
Oral Abstract 153: AAV-mediated overexpression of cannabinoid CB1 receptors preserves functional responses in a mouse model of retinitis pigmentosa

Scientific Sessions
iPSCs and Disease Modelling

Chairs: to be defined
Stevens Rehen, Instituto D'Or
Patricia Braga, USP
Oral Abstract 37: Bioengineering a human lung-on-a-chip platform toward immune-informed preclinical modeling of pulmonary advanced therapies
Oral Abstract 66: Development and validation of a CAPN1 knockout SH-SY5Y cell model via CRISPR-Cas9 for SPG76 studies

16:00 - 16:30

Coffee Break

16:30 - 17:45
Scientific Sessions
CAR-T for Onco and Immune Diseases

Chairs: to be defined
Diego Villa Clé, USP-RP
Marina Carolina de Oliveira Rodrigues, USP-RP
Lorena Lôbo de Figueiredo Pontes, USP-RP

Scientific Sessions
Bioengineering and Tissue Engineering

Chairs: to be defined
Marlon Lemos Dias, UFRJ
Silvya Stuchi Maria-Engler, USP
Oral Abstract 19: Experimental evolution of Zika virus for adaptation in differentiated cells of glioblastoma to enhance oncolytic activity
Oral Abstract 24: Air-jet-generated alginate microgels enable controlled and functional release of AAV vectors for gene therapy applications

17:45 - 18:10

Transition Break

Transition Break / Room Reset

18:10 - 19:10
Evening Grand Rounds

Gene Therapy - Translation and Clinical Trials
Chairs: to be defined
Jonathan Yen, St. Jude Children's Research Hospital
Leszek Lisowski, CMRI / Gene2Cure

19:10 – 20:40

Poster Session I

PROGRAM

DAY 02

NOVEMBER 4, 2026
07:30 – 08:30

Association Meeting

ABTCel-Gen (ABTA) General Assembly

08:30 – 09:15
Industry Workshops
Beckman

Industry Workshops
MaxCyte

09:15 – 10:30
Scientific Sessions
Novel Tools in Gene Editing

Chairs: to be defined
Angela Saito — CNPEM
Davi Coe Torres — Hospital Israelita Albert Einstein
Oral Abstract 107: Sustained reactivation of fetal hemoglobin by adenine base editors in human hematopoietic stem cells for sickle cell disease
Oral Abstract 28: Gene therapy with AAV9 in cellular models for glutaric acidemia type I developed via CRISPR/Cas9 gene editing

Scientific Sessions
GMP Manufacturing

Chairs: to be defined
Lucia Silla — HCPA-UFRGS
Mariana Marques — Hospital Albert Einstein
Oral Abstract 88: Lentiviral vector platform based on packaging cell line engineering and GMP-oriented process development
Oral Abstract 76: Establishing GMP-compliant CAR-T cell manufacturing at INCA for an upcoming pediatric clinical trial in Brazil

10:30 – 11:00

Coffee Break

11:00 – 12:15
Scientific Sessions
Non-Viral Delivery

Chairs: to be defined
Leonardo Martins — University of Antwerp
Ana Paula Dinis Ano Bom — Bio-Manguinhos
Oral Abstract 170: Optimization and preclinical validation of an mRNA-LNP vaccine candidate against Chikungunya virus
Oral Abstract 57: Scaling up the non-viral production of CD19 CAR-T cells using a minicircle-based Sleeping Beauty transposon system

Scientific Sessions
Regulatory Advances in Brazil

Chairs: to be defined
Lara Cristina Pereira — ANVISA
Luciana Piano — ARO-Einstein — Nova Regulamentação em Pesquisa Clínica
Mônica Felts — Diretora Científica, CNPq

12:15 – 13:45
Industry Workshops
Terumo

Workshop window: 12:45 – 13:30

Industry Workshops
Fundação Butantan

Workshop window: 12:45 – 13:30

13:45 – 15:00
INCT/CCTA-Sponsored Scientific Sessions
Advanced Therapies for Cancer: Oncolytic Adenovirus and Nanoparticles

Chairs: to be defined
Sponsored by INTERGEN
Juan Fueyo — MD Anderson Cancer Center
Candelaria Gomez-Manzano — MD Anderson Cancer Center
Wagner José Fávaro — UNICAMP

INCT/CCTA-Sponsored Scientific Sessions
From Science to Access: How Regulation, Innovation and Business Are Shaping Advanced Therapies

Chairs: to be defined
Sponsored by CCTA-EMBRAPII
Lucia Nassif Kerbauy — Hospital Israelita Albert Einstein
Augusto Barbosa Junior — Hospital Israelita Albert Einstein
Eduardo Ferreira de Carvalho Netto — Hospital Israelita Albert Einstein

15:00 - 16:15
Scientific Sessions
Novel CAR-Based Therapies

Chairs: to be defined
Thiago Aparecido Silva - UNESP-Araraquara
Rodrigo Nalio Ramos  - Instituto D'Or
Oral Abstract 14: A Lentiviral EDV Platform for simultaneous CAR Engineering and CRISPR Gene Editing in Primary T and NK Cells
Oral Abstract 79: Cell therapy targeting fungal pathogens: optimization of Mannan-Specific Chimeric Antigen Receptor (M-CAR)

Scientific Sessions
RNA/DNA based therapeutic strategies

Chairs: to be defined
Ricardo Titze - UnB
Tatiana Martins Tilli - Fiocruz
Oral Abstract 42: Isoform-resolved lncRNA remodeling as a secondary readout of SCN2A dosage and CRISPRa-mediated activation in human iPSC-derived cortical excitatory neurons
Oral Abstract 34: From cells to patients: gene therapy with p14ARF and interferon-? reveals antitumor and immunomodulatory mechanisms in canine neoplasms

16:15 - 16:45

Coffee Break

16:45 - 17:45
Grand Rounds

Mesenchymal Stem Cells
Chair: Tatiana Maron Gutierrez - Fiocruz
Daniel Weiss - University of Vermont
Patricia Rocco - UFRJ

17:45 - 18:45
Evening Grand Rounds

IGI Session
Chair: Bruno Solano de Freitas Souza - Instituto D'Or
Ross Wilson - Innovative Genomics Institute
Fyodor Urnov - UC Berkeley

18:45 – 20:15

Poster Session II

PROGRAM

DAY 03

NOVEMBER 5, 2026
08:30 – 09:15
Industry Workshops
Illumina

Industry Workshops
Miltenyi Biotec - Cytogenics

09:15 - 10:30
Scientific Sessions
Extracellular Vesicles

Chairs: to be defined
Fernanda Ferreira Cruz, UFRJ
Bruno Solano de Freitas Souza, Instituto D'Or
Oral Abstract 59: Investigation of the neuroprotective role of extracellular vesicles from physical exercise and associated with FNDC5/irisin in preclinical models of Alzheimer's disease
Oral Abstract 104: 3D Bioprinted Wound Dressings Containing 5-Azacytidine-Preconditioned Human Umbilical Cord Mesenchymal Stromal Cells for the Treatment of Severe Cutaneous Wounds in a Murine Model of Sickle Cell Disease

Scientific Sessions
In Vivo Gene Therapy

Chairs: to be defined
Hilda Petrs-Silva, UFRJ
Guilherme Baldo, UFRGS
Oral Abstract 17: Construction and evaluation of an HSV-1-based oncolytic virus expressing the pro-apoptotic protein sFTRAIL, for the treatment of head and neck tumors
Oral Abstract 146: Therapeutic DNA vaccination targeting HPV16 E5 and E7 oncoproteins: evaluation of different immunization regimens in a preclinical tumor model

10:30 – 11:00

Coffee Break

11:00 – 12:00
Grand Rounds

Past, Present and Future of AAVs
Chairs: to be defined
To be defined
Arun Srivastava, University of Florida

12:00 – 13:30
Industry Workshops
ScaleReady

Workshop window: 12:00 – 12:45

Industry Workshops
Thermo Fisher Scientific

Workshop window: 12:00 – 12:45

13:30 – 14:45
Scientific Sessions
Cell Therapy for Leukemias

Chairs: to be defined
Stephan Kadauke, CHOP
Juliana Dias, University College London
Oral Abstract 142: Phage display selection of scFvs specific for the HER2 S310F mutation from rationally designed libraries based on pertuzumab
Oral Abstract 6: Engineering CAR-T cells to enhance tumor infiltration in solid tumors

Scientific Sessions
Clinical Applications of Gene Therapy in Brazil

Chairs: to be defined
Juliana Maria Ferraz Salum, Escola Paulista de Medicina / UNIFESP
Jonas Alex Morales, UFRGS
Oral Abstract 187: Will It Reach Patients? An AI model predicts clinical translation of gene therapies from modifiable preclinical design choices
Oral Abstract 198: Safety and Preliminary Efficacy of a Brazil-Developed CMV pp65-Specific T-Cell Therapy for Clinically Significant CMV Infection After Allogeneic Hematopoietic Stem Cell Transplantation: Interim Results of a Phase I Study

14:45 – 16:00
INCT-Sponsored Scientific Sessions
Gene Therapy for Oncology

Chairs: to be defined
Sponsored by ONCOTTGEN
André Silva Pimentel, PUCRS
Alfeu Zanotto-Filho, UFSC
Pedro Pires Goulart Guimarães, UFMG

INCT-Sponsored Scientific Sessions
3D Modelling for Complex Diseases

Chairs: to be defined
Sponsored by INCT-Model3D
Marcelo Lazzaron Lamers, UFRGS
Fabio Papes, UNICAMP
Vanessa Morais Freitas, USP

16:00 – 16:30

Closing Session — Award Announcements

Speaker Templates

Prepare your presentation using the CEL-GEN 2026 visual identity. Choose one of the templates below and download the editable PowerPoint file to customize your slides.


AVISO IMPORTANTE
Informamos que a relação dos trabalhos científicos apresentados no CEL-GEN 2026 encontra-se disponível ao final do Livro de Programação, em formato simplificado, devido a limitações técnicas do sistema eletrônico de submissão utilizado. A Comissão Organizadora reconhece essas limitações e esclarece que as informações completas dos trabalhos, incluindo títulos e autoria, serão devidamente contempladas nos certificados de apresentação. Para assegurar a emissão correta dos certificados, solicitamos aos autores que encaminhem o resumo completo, em formato Word (.docx), à Secretaria da ABTCel-Gen, por meio do e-mail (contato@abtcelgen.org.br).

Agradecemos a compreensão e a colaboração de todos. Comissão Organizadora | CEL-GEN 2026

IMPORTANT NOTICE
Please be informed that the list of scientific abstracts presented at CEL-GEN 2026 is available at the end of the Program Book in a simplified format due to technical limitations of the electronic submission system. The Organizing Committee acknowledges these limitations and wishes to clarify that complete information for each contribution, including the full title and all authors, will be accurately reflected in the corresponding presentation certificates. To ensure the accurate issuance of these certificates, we kindly request that authors submit their complete abstracts in Word format (.docx) to the ABTCel-Gen Secretariat via email e-mail (contato@abtcelgen.org.br).

We sincerely appreciate your understanding and cooperation. Organizing Committee | CEL-GEN 2026

GOLD SPONSOR

  • Bio-Manguinhos
  • Insttituto Butantan
  • Merck
  • Scale Ready
  • Terumo Blood and Cell Technologies
  • Vector Builder

SILVER SPONSOR

  • CytoGenics
  • Maxcyte
  • Thermofisher

BRONZE SPONSOR

  • Corning
  • GenScript
  • Interprise
  • Promega
  • Sinapse
  • Synthego

EXHIBITOR

  • Analitica

STARTUP – IOZ

  • Biotech Solutions

SPONSOR SYMPOSIUM

  • Beckman
  • Illumina

SUPPORT

  • FAPERJ
  • Satorius
  • Eppendorf
  • Bayer
  • Caring Cross
  • BS Diagnóstica
  • Hemocentro Ribeirão Preto
  • DBR